Lewis acid-mediated radical cyclization: stereocontrol in cascade radical addition-cyclization-trapping reactions.
نویسندگان
چکیده
An efficient approach for achieving radical cyclizations by using hydroxamate ester as a coordination tether with Lewis acid was studied. The chiral Lewis acid-mediated cascade radical addition-cyclization-trapping reaction proceeded smoothly with good enantio- and diastereoselectivities, providing various chiral γ-lactams.
منابع مشابه
Cascade radical reaction of substrates with a carbon–carbon triple bond as a radical acceptor
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 10 17 شماره
صفحات -
تاریخ انتشار 2012